Networked sensors and measuring systems are increasingly used in industrial production to make manufacturing processes more reliable. So far, acoustic sensor systems have been used in only a limited number of applications. In the ACME 4.0 project, partners from industry and research will investigate the potential of acoustically monitoring machines and production processes. For this purpose, the research partners will develop methods for real-time detection of acoustic events in the high ultrasound range using structure-borne noise sensors. Using methods from computer-based acoustic event detection, the goal is to permit detection of abnormalities or faults in the production process more easily and reliably than in the past. Within the scope of the project, this technology will be tested in quality control in semiconductor production and in fault detection on axial piston pumps. The goal is to develop an energy-autonomous, highly-integrated sensor platform that can be integrated wirelessly in industrial installations.